# About 👥

Genome Nexus is a comprehensive resource integrating variant annotations from [more than a dozen sources](https://docs.genomenexus.org/annotation-sources) relevant to cancer. The annotations can be accessed through a performant [application programming interface](https://docs.genomenexus.org/api) and an [intuitive user interface](https://www.genomenexus.org/), supporting various use cases of variant interpretation. It is freely available under an open source license and can be installed in a private cloud or local environment and integrated with local institutional resources.

Genome Nexus is developed at [Memorial Sloan Kettering Cancer Center](http://www.mskcc.org/) (MSK) and has received several contributions from [The Hyve](http://thehyve.nl/). The [Genome Nexus website](https://www.genomenexus.org/) is hosted by the [Center for Molecular Oncology](http://www.mskcc.org/research/molecular-oncology) at MSK. The software is available under an open source license via [GitHub](https://github.com/genome-nexus).

### How do I cite Genome Nexus?

When using Genome Nexus, please cite [de Bruijn et al., JCO CCI 2022](https://ascopubs.org/doi/abs/10.1200/CCI.21.00144).

Genome Nexus aggregates variant annotation from various sources. See this [documentation](https://docs.genomenexus.org/pages/-LmQuewDTBW0ft2NQkFz#annotation-sources🗄️) for all supported annotation sources. Remember to also cite the underlying annotation sources you are using.

### Current Funding

* [Marie-José and Henry R. Kravis Center for Molecular Oncology at MSK](http://www.mskcc.org/research/molecular-oncology)

### Past Funding

* [The Fund for Innovation in Cancer Informatics](https://www.the-ici-fund.org/)

### Contributors

**Memorial Sloan Kettering Cancer Center, New York, USA**

* Ino de Bruijn
* Onur Sumer
* Xiang Li
* Angelica Ochoa
* Manda Wilson
* Robert Sheridan
* Avery Wang
* Hongxin Zhang
* Aaron Lisman
* Benjamin Gross
* Nikolaus Schultz
* Jianjiong Gao

**The Hyve, the Netherlands**

* Sander Rodenburg
* Pieter Lukasse
* Sjoerd van Hagen

**Alumni**

* Cyriac Kandoth
* Zachary Heins
* Sander Tan
* Ananthan Sadagopan
* Alice Thum
* Emily Zhang


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# Agent Instructions: Querying This Documentation

If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question.

Perform an HTTP GET request on the current page URL with the `ask` query parameter:

```
GET https://docs.genomenexus.org/about.md?ask=<question>
```

The question should be specific, self-contained, and written in natural language.
The response will contain a direct answer to the question and relevant excerpts and sources from the documentation.

Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.