About 👥
Genome Nexus is a comprehensive resource integrating variant annotations from more than a dozen sources relevant to cancer. The annotations can be accessed through a performant application programming interface and an intuitive user interface, supporting various use cases of variant interpretation. It is freely available under an open source license and can be installed in a private cloud or local environment and integrated with local institutional resources.
Genome Nexus is developed at Memorial Sloan Kettering Cancer Center (MSK) and has received several contributions from The Hyve. The Genome Nexus website is hosted by the Center for Molecular Oncology at MSK. The software is available under an open source license via GitHub.
How do I cite Genome Nexus?
When using Genome Nexus, please cite de Bruijn et al., JCO CCI 2022.
Genome Nexus aggregates variant annotation from various sources. See this documentation for all supported annotation sources. Remember to also cite the underlying annotation sources you are using.
Current Funding
Past Funding
Contributors
Memorial Sloan Kettering Cancer Center, New York, USA
Ino de Bruijn
Onur Sumer
Xiang Li
Angelica Ochoa
Manda Wilson
Robert Sheridan
Avery Wang
Hongxin Zhang
Aaron Lisman
Benjamin Gross
Nikolaus Schultz
Jianjiong Gao
The Hyve, the Netherlands
Sander Rodenburg
Pieter Lukasse
Sjoerd van Hagen
Alumni
Cyriac Kandoth
Zachary Heins
Sander Tan
Ananthan Sadagopan
Alice Thum
Emily Zhang
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