# About 👥

Genome Nexus is a comprehensive resource integrating variant annotations from [more than a dozen sources](https://docs.genomenexus.org/annotation-sources) relevant to cancer. The annotations can be accessed through a performant [application programming interface](https://docs.genomenexus.org/api) and an [intuitive user interface](https://www.genomenexus.org/), supporting various use cases of variant interpretation. It is freely available under an open source license and can be installed in a private cloud or local environment and integrated with local institutional resources.

Genome Nexus is developed at [Memorial Sloan Kettering Cancer Center](http://www.mskcc.org/) (MSK) and has received several contributions from [The Hyve](http://thehyve.nl/). The [Genome Nexus website](https://www.genomenexus.org/) is hosted by the [Center for Molecular Oncology](http://www.mskcc.org/research/molecular-oncology) at MSK. The software is available under an open source license via [GitHub](https://github.com/genome-nexus).

### How do I cite Genome Nexus?

When using Genome Nexus, please cite [de Bruijn et al., JCO CCI 2022](https://ascopubs.org/doi/abs/10.1200/CCI.21.00144).

Genome Nexus aggregates variant annotation from various sources. See this [documentation](https://docs.genomenexus.org/annotation-sources#annotation-sources🗄️) for all supported annotation sources. Remember to also cite the underlying annotation sources you are using.

### Current Funding

* [Marie-José and Henry R. Kravis Center for Molecular Oncology at MSK](http://www.mskcc.org/research/molecular-oncology)

### Past Funding

* [The Fund for Innovation in Cancer Informatics](https://www.the-ici-fund.org/)

### Contributors

**Memorial Sloan Kettering Cancer Center, New York, USA**

* Ino de Bruijn
* Onur Sumer
* Xiang Li
* Angelica Ochoa
* Manda Wilson
* Robert Sheridan
* Avery Wang
* Hongxin Zhang
* Aaron Lisman
* Benjamin Gross
* Nikolaus Schultz
* Jianjiong Gao

**The Hyve, the Netherlands**

* Sander Rodenburg
* Pieter Lukasse
* Sjoerd van Hagen

**Alumni**

* Cyriac Kandoth
* Zachary Heins
* Sander Tan
* Ananthan Sadagopan
* Alice Thum
* Emily Zhang